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Sulfur-fluoride exchange (SuFEx)-enabled lead discovery of AChE inhibitors by fragment linking strategies.
Zhang, Ziwen; Zhang, Shi-Long; Wu, Chengyao; Li, Huan-Huan; Zha, Liang; Shi, Jingbo; Liu, Xinhua; Qin, Hua-Li; Tang, Wenjian.
Afiliação
  • Zhang Z; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
  • Zhang SL; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
  • Wu C; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
  • Li HH; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
  • Zha L; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
  • Shi J; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China.
  • Liu X; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China. Electronic address: xhliuhx@163.com.
  • Qin HL; School of Chemistry, Chemical Engineering and Life Science, Wuhan University of Technology, Wuhan, 430070, China. Electronic address: qinhuali@whut.edu.cn.
  • Tang W; School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Medical University, Hefei, 230032, China. Electronic address: ahmupharm@126.com.
Eur J Med Chem ; 257: 115502, 2023 Sep 05.
Article em En | MEDLINE | ID: mdl-37224761
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Enxofre / Fluoretos Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Enxofre / Fluoretos Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article