An Alzheimer's disease risk variant in <i>TTC3</i> modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons.

Cukier, Holly N; Duarte, Carolina L; Laverde-Paz, Mayra J; Simon, Shaina A; Van Booven, Derek J; Miyares, Amanda T; Whitehead, Patrice L; Hamilton-Nelson, Kara L; Adams, Larry D; Carney, Regina M; Cuccaro, Michael L; Vance, Jeffery M; Pericak-Vance, Margaret A; Griswold, Anthony J; Dykxhoorn, Derek M

An Alzheimer's disease risk variant in TTC3 modifies the actin cytoskeleton organization and the PI3K-Akt signaling pathway in iPSC-derived forebrain neurons.

Cukier, Holly N; Duarte, Carolina L; Laverde-Paz, Mayra J; Simon, Shaina A; Van Booven, Derek J; Miyares, Amanda T; Whitehead, Patrice L; Hamilton-Nelson, Kara L; Adams, Larry D; Carney, Regina M; Cuccaro, Michael L; Vance, Jeffery M; Pericak-Vance, Margaret A; Griswold, Anthony J; Dykxhoorn, Derek M.

bioRxiv ; 2023 May 25.

Article em En | MEDLINE | ID: mdl-37292815

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Guideline / Risk_factors_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Etiology_studies / Guideline / Risk_factors_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article