Pathological Roles of INPP5D in Alzheimer's Disease.

Chu, Yung Ning; Akahori, Aika; Takatori, Sho; Tomita, Taisuke

Chu, Yung Ning; Akahori, Aika; Takatori, Sho; Tomita, Taisuke.

Afiliação

Chu YN; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Akahori A; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Takatori S; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.
Tomita T; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan. taisuke@mol.f.u-tokyo.ac.jp.

Adv Exp Med Biol ; 1423: 289-301, 2023.

Article em En | MEDLINE | ID: mdl-37525057

Assuntos

Doença de Alzheimer; Animais; Camundongos; Hidrolases Anidrido Ácido/metabolismo; Doença de Alzheimer/metabolismo; Peptídeos beta-Amiloides/genética; Peptídeos beta-Amiloides/metabolismo; Modelos Animais de Doenças; Microglia/patologia; Placa Amiloide/patologia

Palavras-chave

Alzheimer's disease (AD); Amyloid hypothesis; Amyloid ß (Aß); Genetic risk factor; Inositol polyphosphate-5-polyphosphatase D (INPP5D); Microglia; Phosphoinositide; Tau; Triggering receptor expressed on myeloid cells 2 (TREM2)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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