Perioperative administration of dexamethasone to prevent postoperative shivering: a systematic review and meta-analysis of randomized controlled trials.
J Int Med Res
; 51(8): 3000605231187805, 2023 Aug.
Article
em En
| MEDLINE
| ID: mdl-37534441
ABSTRACT
OBJECTIVE:
To evaluate the perioperative administration of dexamethasone to prevent postoperative shivering.METHODS:
We searched PubMed, Embase, Google Scholar, Web of Science, and Cochrane Library for relevant studies of the administration of dexamethasone to prevent postoperative shivering published through 31 May 2023. The primary outcome was the incidence of postoperative shivering. Secondary outcomes comprised the incidence of postoperative nausea, vomiting, and postoperative nausea and vomiting (PONV). RevMan 5.3 software was used for the data analysis.RESULTS:
We included 12 randomized controlled trials (1276 participants). The results revealed a benefit favoring the perioperative administration of dexamethasone to prevent postoperative shivering (relative risk [RR] 0.39; 95% confidence interval [CI] 0.23-0.63), as well as the grade of shivering. The administration of dexamethasone also reduced the incidence of postoperative nausea (RR 0.54; 95% CI 0.39-0.73), postoperative vomiting (RR 0.37; 95% CI 0.20-0.65), and PONV (RR 0.50; 95% CI 0.26-0.95) compared with the control group.CONCLUSION:
This study indicated that perioperative administration of dexamethasone prevented postoperative shivering and decreased the incidence of other complications.PROSPERO registration number CRD42020164488.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Estremecimento
/
Náusea e Vômito Pós-Operatórios
Tipo de estudo:
Clinical_trials
/
Etiology_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article