Sustained release of a highly specific GSK3ß inhibitor SB216763 in the PCL scaffold creates an osteogenic niche for osteogenesis, anti-adipogenesis, and potential angiogenesis.

Gong, Weimin; Li, Molin; Zhao, Lizhou; Wang, Pengtao; Wang, Xiaofang; Wang, Bo; Liu, Xing; Tu, Xiaolin

Gong, Weimin; Li, Molin; Zhao, Lizhou; Wang, Pengtao; Wang, Xiaofang; Wang, Bo; Liu, Xing; Tu, Xiaolin.

Afiliação

Gong W; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing, China.
Li M; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing, China.
Zhao L; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing, China.
Wang P; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing, China.
Wang X; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing, China.
Wang B; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing, China.
Liu X; Department of Orthopedics, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, Children's Hospital of Chongqing Medical University, Chongqing, China.
Tu X; Laboratory of Skeletal Development and Regeneration, Institute of Life Sciences, Chongqing Medical University, Chongqing, China.

Front Bioeng Biotechnol ; 11: 1215233, 2023.

Article em En | MEDLINE | ID: mdl-37576993