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Myeloid-specific blockade of notch signaling alleviates dopaminergic neurodegeneration in Parkinson's disease by dominantly regulating resident microglia activation through NF-κB signaling.
Liang, Shi-Qian; Li, Peng-Hui; Hu, Yi-Yang; Zhao, Jun-Long; Shao, Fang-Ze; Kuang, Fang; Ren, Kai-Xi; Wei, Tiao-Xia; Fan, Fan; Feng, Lei; Han, Hua; Qin, Hong-Yan.
Afiliação
  • Liang SQ; State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
  • Li PH; State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
  • Hu YY; Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
  • Zhao JL; State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
  • Shao FZ; State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
  • Kuang F; State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
  • Ren KX; Department of Neurobiology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
  • Wei TX; Department of Neurology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
  • Fan F; State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
  • Feng L; State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
  • Han H; State Key Laboratory of Cancer Biology, Department of Medical Genetics and Developmental Biology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
  • Qin HY; Department of Biochemistry and Molecular Biology, School of Basic Medicine, Fourth Military Medical University, Xi'an, China.
Front Immunol ; 14: 1193081, 2023.
Article em En | MEDLINE | ID: mdl-37680624
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / NF-kappa B Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / NF-kappa B Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article