Discovery of novel reversible inhibitor of DprE1 based on benzomorpholine for the treatment of tuberculosis.

Xiang, Wang; He, Hualong; Duan, Xianjie; He, Zhiqun; Xu, Xinyue; Liao, Mengya; Teng, Fei; Li, Xiao; Luo, Tianwen; Zeng, Jumei; Yu, Luoting; Gao, Chao

Xiang, Wang; He, Hualong; Duan, Xianjie; He, Zhiqun; Xu, Xinyue; Liao, Mengya; Teng, Fei; Li, Xiao; Luo, Tianwen; Zeng, Jumei; Yu, Luoting; Gao, Chao.

Afiliação

Xiang W; State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University , Chengdu, Sichuan, China.
He H; State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University , Chengdu, Sichuan, China.
Duan X; State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University , Chengdu, Sichuan, China.
He Z; West China School of Public Health and West China Fourth Hospital, Sichuan University , Chengdu, Sichuan, China.
Xu X; West China School of Public Health and West China Fourth Hospital, Sichuan University , Chengdu, Sichuan, China.
Liao M; Center of Gerontology and Geriatrics, West China Hospital, Sichuan University , Chengdu, Sichuan, China.
Teng F; State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University , Chengdu, Sichuan, China.
Li X; State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University , Chengdu, Sichuan, China.
Luo T; State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University , Chengdu, Sichuan, China.
Zeng J; West China School of Public Health and West China Fourth Hospital, Sichuan University , Chengdu, Sichuan, China.
Yu L; State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University , Chengdu, Sichuan, China.
Gao C; Center of Infectious Diseases and Laboratory of Human Diseases and Immunotherapies and Institute of Immunology and Inflammation, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University , Chengdu, Sichuan, China.