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Gys1 Antisense Therapy Prevents Disease-Driving Aggregates and Epileptiform Discharges in a Lafora Disease Mouse Model.
Donohue, Katherine J; Fitzsimmons, Bethany; Bruntz, Ronald C; Markussen, Kia H; Young, Lyndsay E A; Clarke, Harrison A; Coburn, Peyton T; Griffith, Laiken E; Sanders, William; Klier, Jack; Burke, Sara N; Maurer, Andrew P; Minassian, Berge A; Sun, Ramon C; Kordasiewisz, Holly B; Gentry, Matthew S.
Afiliação
  • Donohue KJ; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, 40506, USA.
  • Fitzsimmons B; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Carlsbad, CA, 92010, USA.
  • Bruntz RC; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, 40506, USA.
  • Markussen KH; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, 40506, USA.
  • Young LEA; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, 40506, USA.
  • Clarke HA; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, 32610, USA.
  • Coburn PT; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, 40506, USA.
  • Griffith LE; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, 40506, USA.
  • Sanders W; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, 40506, USA.
  • Klier J; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY, 40506, USA.
  • Burke SN; Department of Neuroscience and Center for Cognitive Aging and Memory, University of Florida, Gainesville, FL, 32610, USA.
  • Maurer AP; Department of Neuroscience and Center for Cognitive Aging and Memory, University of Florida, Gainesville, FL, 32610, USA.
  • Minassian BA; Division of Neurology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
  • Sun RC; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, 32610, USA.
  • Kordasiewisz HB; Department of Antisense Drug Discovery, Ionis Pharmaceuticals, Carlsbad, CA, 92010, USA.
  • Gentry MS; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, 32610, USA. matthew.gentry@ufl.edu.
Neurotherapeutics ; 20(6): 1808-1819, 2023 Oct.
Article em En | MEDLINE | ID: mdl-37700152
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Lafora Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Lafora Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article