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SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8+ T cells.
Celada, Sherly I; Lim, Clarice X; Carisey, Alexandre F; Ochsner, Scott A; Arce Deza, Carlos F; Rexie, Praveen; Poli De Frias, Fernando; Cardenas-Castillo, Rafael; Polverino, Francesca; Hengstschläger, Markus; Tsoyi, Konstantin; McKenna, Neil J; Kheradmand, Farrah; Weichhart, Thomas; Rosas, Ivan O; Van Kaer, Luc; Celada, Lindsay J.
Afiliação
  • Celada SI; Department of Biological Sciences, Tennessee State University, Nashville, TN 37209, USA.
  • Lim CX; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna 1090, Austria.
  • Carisey AF; William T. Shearer Center for Human Immunobiology, Texas Children's Hospital, Houston, TX 77030, USA.
  • Ochsner SA; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Arce Deza CF; Department of Cell and Molecular Biology, St. Jude Children's Hospital, Memphis, TN 38105, USA.
  • Rexie P; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Poli De Frias F; Department of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Cardenas-Castillo R; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna 1090, Austria.
  • Polverino F; Department of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Hengstschläger M; Mount Sinai Medical Center, Miami Beach, FL 33140, USA.
  • Tsoyi K; Department of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • McKenna NJ; Department of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Kheradmand F; Center of Pathobiochemistry and Genetics, Institute of Medical Genetics, Medical University of Vienna, Vienna 1090, Austria.
  • Weichhart T; Department of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Rosas IO; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Van Kaer L; Department of Medicine, Section of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Celada LJ; Center for Translational Research on Inflammatory Diseases, Michael E. DeBakey VA Medical Center, Houston, TX 77030, USA.
Sci Transl Med ; 15(713): eade2581, 2023 09 13.
Article em En | MEDLINE | ID: mdl-37703351
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoidose / Linfócitos T CD8-Positivos Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sarcoidose / Linfócitos T CD8-Positivos Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article