Genic constraint against nonsynonymous variation across the mouse genome.

Powell, George; Simon, Michelle M; Pulit, Sara; Mallon, Ann-Marie; Lindgren, Cecilia M

Powell, George; Simon, Michelle M; Pulit, Sara; Mallon, Ann-Marie; Lindgren, Cecilia M.

Afiliação

Powell G; Li Ka Shing Centre for Health Information and Discovery, Big Data Institute, University of Oxford, Oxford, UK. gjp15@ic.ac.uk.
Simon MM; Mammalian Genetics Unit, MRC Harwell Institute, Oxfordshire, OX11 0RD, UK. gjp15@ic.ac.uk.
Pulit S; Mammalian Genetics Unit, MRC Harwell Institute, Oxfordshire, OX11 0RD, UK.
Mallon AM; Li Ka Shing Centre for Health Information and Discovery, Big Data Institute, University of Oxford, Oxford, UK.
Lindgren CM; Mammalian Genetics Unit, MRC Harwell Institute, Oxfordshire, OX11 0RD, UK.

BMC Genomics ; 24(1): 562, 2023 Sep 22.

Article em En | MEDLINE | ID: mdl-37736706

Assuntos

Músculos; Mytilidae; Humanos; Animais; Camundongos; Modelos Animais de Doenças; Tamanho da Amostra; Sequenciamento Completo do Genoma; Mamíferos

Palavras-chave

Mouse models; Negative selection; Selective constraint; Synonymous and nonsynonymous mutation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mytilidae / Músculos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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