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Efficacy and safety of a synthetic biotic for treatment of phenylketonuria: a phase 2 clinical trial.
Vockley, Jerry; Sondheimer, Neal; Puurunen, Marja; Diaz, George A; Ginevic, Ilona; Grange, Dorothy K; Harding, Cary; Northrup, Hope; Phillips, John A; Searle, Shawn; Thomas, Janet A; Zori, Roberto; Denney, William S; Ernst, Sharon L; Humphreys, Kristina; McWhorter, Nicole; Kurtz, Caroline; Brennan, Aoife M.
Afiliação
  • Vockley J; Schools of Medicine and Public Health, Departments of Pediatrics and Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
  • Sondheimer N; Synlogic Inc., Cambridge, MA, USA. neal.sondheimer@synlogictx.com.
  • Puurunen M; Synlogic Inc., Cambridge, MA, USA.
  • Diaz GA; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Ginevic I; Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Grange DK; Division of Genetics and Genomic Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
  • Harding C; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR, USA.
  • Northrup H; Department of Pediatrics, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth) and Children's Memorial Hermann Hospital, Houston, TX, USA.
  • Phillips JA; Vanderbilt University Medical Center, Nashville, TN, USA.
  • Searle S; Early Clinical & Bioanalytical Research, ICON, Salt Lake City, UT, USA.
  • Thomas JA; Section of Clinical Genetics and Metabolism, Department of Pediatrics, Children's Hospital Colorado and University of Colorado School of Medicine, Aurora, CO, USA.
  • Zori R; Division of Clinical Genetics and Metabolism, University of Florida, Gainesville, FL, USA.
  • Denney WS; Synlogic Inc., Cambridge, MA, USA.
  • Ernst SL; Synlogic Inc., Cambridge, MA, USA.
  • Humphreys K; Synlogic Inc., Cambridge, MA, USA.
  • McWhorter N; Synlogic Inc., Cambridge, MA, USA.
  • Kurtz C; Synlogic Inc., Cambridge, MA, USA.
  • Brennan AM; Synlogic Inc., Cambridge, MA, USA.
Nat Metab ; 5(10): 1685-1690, 2023 Oct.
Article em En | MEDLINE | ID: mdl-37770764
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilalanina / Fenilcetonúrias Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenilalanina / Fenilcetonúrias Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2023 Tipo de documento: Article