How non-alcoholic fatty liver disease and cirrhosis affect the heart.
Hepatol Int
; 17(6): 1333-1349, 2023 Dec.
Article
em En
| MEDLINE
| ID: mdl-37770804
ABSTRACT
Liver diseases affect the heart and the vascular system. Cardiovascular complications appear to be a leading cause of death in patients with non-alcoholic fatty liver disease (NAFLD) and cirrhosis. The predominant histological changes in the liver range from steatosis to fibrosis to cirrhosis, which can each affect the cardiovascular system differently. Patients with cirrhotic cardiomyopathy (CCM) and NAFLD are at increased risk of impaired systolic and diastolic dysfunction and for suffering major cardiovascular events. However, the pathophysiological mechanisms behind these risks differ depending on the nature of the liver disease. Accurate assessment of symptoms by contemporary diagnostic modalities is essential for identifying patients at risk, for evaluating candidates for treatment, and prior to any invasive procedures. This review explores current perspectives within this field.
Palavras-chave
Arterial vasodilatation; Cardiac events; Cardiovascular dysfunction; Cirrhosis; Cirrhotic cardiomyopathy; Diastolic dysfunction; Heart failure; Hyperdynamic circulation; Liver transplantation; Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Portal hypertension; QT interval; Systolic dysfunction
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hepatopatia Gordurosa não Alcoólica
/
Cardiomiopatias
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article