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CHIT1-positive microglia drive motor neuron ageing in the primate spinal cord.
Sun, Shuhui; Li, Jiaming; Wang, Si; Li, Jingyi; Ren, Jie; Bao, Zhaoshi; Sun, Le; Ma, Xibo; Zheng, Fangshuo; Ma, Shuai; Sun, Liang; Wang, Min; Yu, Yan; Ma, Miyang; Wang, Qiaoran; Chen, Zhiyuan; Ma, He; Wang, Xuebao; Wu, Zeming; Zhang, Hui; Yan, Kaowen; Yang, Yuanhan; Zhang, Yixin; Zhang, Sheng; Lei, Jinghui; Teng, Zhao-Qian; Liu, Chang-Mei; Bai, Ge; Wang, Yan-Jiang; Li, Jian; Wang, Xiaoqun; Zhao, Guoguang; Jiang, Tao; Belmonte, Juan Carlos Izpisua; Qu, Jing; Zhang, Weiqi; Liu, Guang-Hui.
Afiliação
  • Sun S; State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
  • Li J; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
  • Wang S; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.
  • Li J; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.
  • Ren J; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing, China.
  • Bao Z; University of Chinese Academy of Sciences, Beijing, China.
  • Sun L; Advanced Innovation Center for Human Brain Protection, and National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital Capital Medical University, Beijing, China.
  • Ma X; Aging Translational Medicine Center, International Center for Aging and Cancer, Beijing Municipal Geriatric Medical Research Center, Xuanwu Hospital, Capital Medical University, Beijing, China.
  • Zheng F; Aging Biomarker Consortium, Beijing, China.
  • Ma S; The Fifth People's Hospital of Chongqing, Chongqing, China.
  • Sun L; State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
  • Wang M; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.
  • Yu Y; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.
  • Ma M; University of Chinese Academy of Sciences, Beijing, China.
  • Wang Q; Aging Biomarker Consortium, Beijing, China.
  • Chen Z; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.
  • Ma H; CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing, China.
  • Wang X; University of Chinese Academy of Sciences, Beijing, China.
  • Wu Z; Aging Biomarker Consortium, Beijing, China.
  • Zhang H; Key Laboratory of RNA Science and Engineering, Beijing Institute of Genomics, Chinese Academy of Sciences and China National Center for Bioinformation, Beijing, China.
  • Yan K; Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
  • Yang Y; The Chinese Glioma Genome Atlas, Beijing, China.
  • Zhang Y; Beijing Institute of Brain Disorders, Capital Medical University, Beijing, China.
  • Zhang S; MAIS, State Key Laboratory of Multimodal Artificial Intelligence Systems, Institute of Automation, Chinese Academy of Sciences, Beijing, China.
  • Lei J; School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China.
  • Teng ZQ; College of Medicine and Biomedical Information Engineering, Northeastern University, Shenyang, China.
  • Liu CM; The Fifth People's Hospital of Chongqing, Chongqing, China.
  • Bai G; State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
  • Wang YJ; Institute for Stem Cell and Regeneration, Chinese Academy of Sciences, Beijing, China.
  • Li J; Beijing Institute for Stem Cell and Regenerative Medicine, Beijing, China.
  • Wang X; University of Chinese Academy of Sciences, Beijing, China.
  • Zhao G; Aging Biomarker Consortium, Beijing, China.
  • Jiang T; Aging Biomarker Consortium, Beijing, China.
  • Belmonte JCI; The MOH Key Laboratory of Geriatrics, Beijing Hospital, National Center of Gerontology, Beijing, China.
  • Qu J; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
  • Zhang W; University of Science and Technology of China, Hefei, China.
  • Liu GH; State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Nature ; 624(7992): 611-620, 2023 Dec.
Article em En | MEDLINE | ID: mdl-37907096
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Primatas / Medula Espinal / Quitinases / Senescência Celular / Microglia / Neurônios Motores Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Primatas / Medula Espinal / Quitinases / Senescência Celular / Microglia / Neurônios Motores Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article