Enzymatic Fluoromethylation as a Tool for ATP-Independent Ligation.

Peng, Jiaming; Hughes, Gregory R; Müller, Manuel M; Seebeck, Florian P

Peng, Jiaming; Hughes, Gregory R; Müller, Manuel M; Seebeck, Florian P.

Afiliação

Peng J; Department of Chemistry, University of Basel, Mattenstrasseâ24a, 4002, Basel, Switzerland.
Hughes GR; Department of Chemistry, King's College London, Britannia House, 7 Trinity Street, SE1 1DB, London, UK.
Müller MM; Department of Chemistry, King's College London, Britannia House, 7 Trinity Street, SE1 1DB, London, UK.
Seebeck FP; Department of Chemistry, University of Basel, Mattenstrasseâ24a, 4002, Basel, Switzerland.

Angew Chem Int Ed Engl ; 63(1): e202312104, 2024 Jan 02.

Article em En | MEDLINE | ID: mdl-37955592

Assuntos

Amidas; Metiltransferases; Metiltransferases/metabolismo; Metilação; Amidas/química; S-Adenosilmetionina/química; Ácidos Carboxílicos; Trifosfato de Adenosina/metabolismo; Biocatálise

Palavras-chave

Fluorine Biocatalysis; Methyltransferase Biocatalysis; Native Chemical Ligation; Post Translational Modification; Protein Synthesis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Amidas / Metiltransferases Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Amidas / Metiltransferases Idioma: En Ano de publicação: 2024 Tipo de documento: Article