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Creation of Novel Sensitive Probe Substrate and Moderate Inhibitor Models for a Comprehensive Prediction of CYP2C8 Interactions for Tucatinib.
Templeton, Ian E; Rowland-Yeo, Karen; Jones, Hannah M; Endres, Christopher J; Topletz-Erickson, Ariel R; Sun, Hao; Lee, Anthony J.
Afiliação
  • Templeton IE; Certara, UK Ltd. (Simcyp Division), Sheffield, UK.
  • Rowland-Yeo K; Certara, UK Ltd. (Simcyp Division), Sheffield, UK.
  • Jones HM; Certara, UK Ltd. (Simcyp Division), Sheffield, UK.
  • Endres CJ; Quantitative Pharmacology and Disposition, Seagen Inc., Bothell, Washington, USA.
  • Topletz-Erickson AR; Quantitative Pharmacology and Disposition, Seagen Inc., Bothell, Washington, USA.
  • Sun H; Quantitative Pharmacology and Disposition, Seagen Inc., Bothell, Washington, USA.
  • Lee AJ; Quantitative Pharmacology and Disposition, Seagen Inc., Bothell, Washington, USA.
Clin Pharmacol Ther ; 115(2): 299-308, 2024 02.
Article em En | MEDLINE | ID: mdl-37971208
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxazóis / Piridinas / Quinazolinas / Genfibrozila / Inibidores do Citocromo P-450 CYP2C8 Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxazóis / Piridinas / Quinazolinas / Genfibrozila / Inibidores do Citocromo P-450 CYP2C8 Limite: Humans Idioma: En Ano de publicação: 2024 Tipo de documento: Article