Modelling 3D Tumour Microenvironment In Vivo: A Tool to Predict Cancer Fate.
Curr Issues Mol Biol
; 45(11): 9076-9083, 2023 Nov 14.
Article
em En
| MEDLINE
| ID: mdl-37998746
ABSTRACT
Recently, many studies demonstrated the fundamental role of the tumour microenvironment (TME) in cancer progression. Here, we describe a method to visualize in 3D the behaviour of tumours in zebrafish embryos. We highlight two major actors of the TME, macrophages and vessels. This valuable tool is transposable to Patient-Derived Xenograft imaging in order to predict the fate of malignant tumours according to the dynamics of their TME.
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MEDLINE
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En
Ano de publicação:
2023
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Article