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COPI vesicle formation and N-myristoylation are targetable vulnerabilities of senescent cells.
McHugh, Domhnall; Sun, Bin; Gutierrez-Muñoz, Carmen; Hernández-González, Fernanda; Mellone, Massimiliano; Guiho, Romain; Duran, Imanol; Pombo, Joaquim; Pietrocola, Federico; Birch, Jodie; Kallemeijn, Wouter W; Khadayate, Sanjay; Dharmalingam, Gopuraja; Vernia, Santiago; Tate, Edward W; Martínez-Barbera, Juan Pedro; Withers, Dominic J; Thomas, Gareth J; Serrano, Manuel; Gil, Jesús.
Afiliação
  • McHugh D; MRC Laboratory of Medical Sciences (LMS), London, UK.
  • Sun B; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London, UK.
  • Gutierrez-Muñoz C; MRC Laboratory of Medical Sciences (LMS), London, UK.
  • Hernández-González F; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London, UK.
  • Mellone M; MRC Laboratory of Medical Sciences (LMS), London, UK.
  • Guiho R; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London, UK.
  • Duran I; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.
  • Pombo J; Department of Pulmonology, ICR, Hospital Clinic, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.
  • Pietrocola F; Instituto de Investigaciones Biomédicas August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
  • Birch J; School of Cancer Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Kallemeijn WW; AstraZeneca, Immuno-Oncology Discovery, Oncology R&D, Cambridge, UK.
  • Khadayate S; Developmental Biology and Cancer Programme, Birth Defects Research Centre, Great Ormond Street Institute of Child Health, University College London, London, UK.
  • Dharmalingam G; MRC Laboratory of Medical Sciences (LMS), London, UK.
  • Vernia S; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London, UK.
  • Tate EW; MRC Laboratory of Medical Sciences (LMS), London, UK.
  • Martínez-Barbera JP; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London, UK.
  • Withers DJ; Karolinska Institute, Department of Biosciences and Nutrition, Huddinge, Sweden.
  • Thomas GJ; MRC Laboratory of Medical Sciences (LMS), London, UK.
  • Serrano M; Institute of Clinical Sciences (ICS), Faculty of Medicine, Imperial College London, London, UK.
  • Gil J; Department of Chemistry, Molecular Sciences Research Hub, London, UK.
Nat Cell Biol ; 25(12): 1804-1820, 2023 Dec.
Article em En | MEDLINE | ID: mdl-38012402
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Senoterapia / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Senoterapia / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article