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Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons.
Hippman, Ryan S; Snead, Amanda M; Petros, Zoe A; Korkmaz-Vaisys, Melissa A; Patel, Sruchi; Sotelo, Daniel; Dobria, Andrew; Salkovski, Maryna; Nguyen, Thu T A; Linares, Ricardo; Cologna, Stephanie M; Gowrishankar, Swetha; Aldrich, Leslie N.
Afiliação
  • Hippman RS; Department of Chemistry, College of Liberal Arts and Sciences, University of Illinois Chicago, 845 W. Taylor Street, Chicago, Illinois 60607, United States.
  • Snead AM; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois Chicago, 808 S. Wood Street, Chicago, Illinois 60612, United States.
  • Petros ZA; Department of Chemistry, College of Liberal Arts and Sciences, University of Illinois Chicago, 845 W. Taylor Street, Chicago, Illinois 60607, United States.
  • Korkmaz-Vaisys MA; Department of Chemistry, College of Liberal Arts and Sciences, University of Illinois Chicago, 845 W. Taylor Street, Chicago, Illinois 60607, United States.
  • Patel S; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois Chicago, 808 S. Wood Street, Chicago, Illinois 60612, United States.
  • Sotelo D; Department of Chemistry, College of Liberal Arts and Sciences, University of Illinois Chicago, 845 W. Taylor Street, Chicago, Illinois 60607, United States.
  • Dobria A; Department of Chemistry, College of Liberal Arts and Sciences, University of Illinois Chicago, 845 W. Taylor Street, Chicago, Illinois 60607, United States.
  • Salkovski M; Department of Chemistry, College of Liberal Arts and Sciences, University of Illinois Chicago, 845 W. Taylor Street, Chicago, Illinois 60607, United States.
  • Nguyen TTA; Department of Chemistry, College of Liberal Arts and Sciences, University of Illinois Chicago, 845 W. Taylor Street, Chicago, Illinois 60607, United States.
  • Linares R; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois Chicago, 808 S. Wood Street, Chicago, Illinois 60612, United States.
  • Cologna SM; Department of Chemistry, College of Liberal Arts and Sciences, University of Illinois Chicago, 845 W. Taylor Street, Chicago, Illinois 60607, United States.
  • Gowrishankar S; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois Chicago, 808 S. Wood Street, Chicago, Illinois 60612, United States.
  • Aldrich LN; Department of Chemistry, College of Liberal Arts and Sciences, University of Illinois Chicago, 845 W. Taylor Street, Chicago, Illinois 60607, United States.
ACS Chem Neurosci ; 14(24): 4363-4382, 2023 Dec 20.
Article em En | MEDLINE | ID: mdl-38069806
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lamina Tipo A / Doença de Alzheimer Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lamina Tipo A / Doença de Alzheimer Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article