Stretching is not essential for managing MS spasticity: A randomized controlled trial.
Mult Scler
; 30(1): 89-102, 2024 Jan.
Article
em En
| MEDLINE
| ID: mdl-38140847
ABSTRACT
BACKGROUND:
Clinical practice, expert opinion, and evidence-based guidelines recommend daily stretching as first-line treatment for multiple sclerosis (MS) spasticity, but this has not been evaluated by fully powered clinical trials.OBJECTIVE:
To determine whether MS Spasticity Take Control (STC), a guideline-based program of spasticity education and stretching exercises has different effects on the impact of spasticity than a control program of different spasticity education and range of motion (ROM) exercises.METHODS:
Ambulatory people with self-reported MS spasticity were randomly assigned to STC or ROM, delivered in same duration, facilitator-led, group classes, face-to-face (F2F) initially and later virtually, due to coronavirus disease 2019 (COVID-19). Multiple Sclerosis Spasticity Scale (MSSS) scores were compared between groups at 1 (primary outcome) and 6 months after interventions.RESULTS:
A total of 231 people enrolled. There was no significant difference in MSSS scores between STC and ROM at 1 month (mean difference = 0.28, 95% (confidence interval (CI)) = [-9.45 to 10.01], p = 0.955). There were significant group mean improvements in MSSS scores and most other outcomes at 1 and 6 months.CONCLUSION:
Education with stretching exercises, the first-line recommended treatment for MS spasticity, and education with ROM exercises may both improve MS spasticity to a similar degree. This study debunks the belief that stretching is essential to managing MS spasticity.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Esclerose Múltipla
/
Espasticidade Muscular
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article