[Research progress of biomarkers of hepatitis B virus and clinical significance].
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
; 40(6): 1242-1248, 2023 Dec 25.
Article
em Zh
| MEDLINE
| ID: mdl-38151949
ABSTRACT
The infection of Hepatitis B virus (HBV) can result in severe consequences, including chronic hepatitis, liver fibrosis, cirrhosis, and even liver cancer. Effective antiviral treatment has the potential to slow down the progression of the disease. HBV serum biomarkers play a crucial role in the dynamic management of chronic hepatitis B (CHB) patients. However, the conventional hepatitis B virus markers, such as hepatitis B serologic testing and HBV DNA, are insufficient to meet the clinical requirements. This review provided a comprehensive overview of the current research on the quantification of HBsAg and anti-HBc, HBV RNA and HBV core-associated antigen, which summarized the crucial role these markers play in the administration of antiviral medications, predicting the efficacy of treatment and anticipating the likelihood of virologic rebound following drug cessation, as well as assessing disease progression in CHB patients.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Hepatite B Crônica
/
Hepatite B
Limite:
Humans
Idioma:
Zh
Ano de publicação:
2023
Tipo de documento:
Article