Electrochemical Biosensor for Protein Concentration Monitoring Using Natural Wood Evaporation for Power Generation.
Anal Chem
; 96(2): 917-925, 2024 01 16.
Article
em En
| MEDLINE
| ID: mdl-38171538
ABSTRACT
A high-sensitivity, low-cost, self-powered biomass electrochemical biosensor based on the "evaporating potential" theory is developed for protein detection. The feasibility of experimental evaluation methods was verified with a probe protein of bovine serum albumin. The sensor was then used to detect lung cancer marker CYFRA21-1, and the potential of our sensor for clinical diagnosis was demonstrated by serum analysis. This work innovatively exploits the osmotic power generation capability of natural wood to construct a promising electrochemical biosensor that was driven by kinetics during testing. The detection methods used for this sensor, chronoamperometry and AC impedance, showed potential for quantitative analysis and specific detection, respectively. Furthermore, the sensor could facilitate new insights into the development of high-sensitivity, low-cost, and easy-to-use electrochemical biosensors.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Madeira
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Técnicas Biossensoriais
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Queratina-19
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Antígenos de Neoplasias
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article