Reconsidering Routine Repeat Group and Screens During Pregnancy-Personalizing Pregnancy Care.
J Obstet Gynaecol Can
; 46(5): 102351, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38199432
ABSTRACT
The group and screen (G&S) are performed in early pregnancy to identify clinically significant antibodies (CSA) that may necessitate fetal monitoring for hemolysis/anemia or affect RhIg eligibility. Guidelines vary, including differences between RhD-positive and negative patients, but typically, the G&S is repeated at 28 weeks, and sometimes pre-delivery. We reviewed data showing a low risk (0.01%-0.43%) of detecting a new CSA in late gestation (late alloimmunization) and the risk of late alloimmunization causing severe hemolysis/anemia is even lower at <0.01%. Routinely repeating a G&S at 28 weeks and delivery may not be necessary for healthy, low-risk pregnancies.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Isoimunização Rh
Tipo de estudo:
Guideline
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article