Leishmaniasis in otorhinolaryngology: an emerging disease and its relationship with anti-tumor necrosis factor-alpha drugs.
Eur Arch Otorhinolaryngol
; 281(5): 2739-2742, 2024 May.
Article
em En
| MEDLINE
| ID: mdl-38453713
ABSTRACT
PURPOSE:
To investigate the clinical manifestations, management and outcomes of Leishmania lesions in the ear-nose-throat (ENT) region, and its relationship with tumor necrosis factor (TNF)-α blocking drugs.METHODS:
Single-center retrospective observational study. Patients diagnosed with cutaneous and mucosal leishmaniasis in the otorhinolaryngologic area at a tertiary referral center over a period of 8 years.RESULTS:
Three cases of Leishmania lesions in the ear and two in the nose were encountered at our institution. All patients were under treatment with TNF-α blocking drugs. Diagnosis was challenging, and it was important to have a clinical suspicion in order to use accurate detection techniques. All patients received systemic treatment and achieved a complete resolution of the lesions.CONCLUSIONS:
With the increasing use of biologic treatments like TNF-α blockers, this type of infection will be increasingly frequent in endemic areas and also worldwide. It is important to include leishmaniasis in the differential diagnosis of inflammatory/infectious lesions in the ENT region.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Otolaringologia
/
Leishmaniose
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Leishmaniose Cutânea
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article