Edible oil based optical clearing for optical coherence tomography angiography imaging.
Microvasc Res
; 154: 104671, 2024 07.
Article
em En
| MEDLINE
| ID: mdl-38460712
ABSTRACT
In optical imaging, optical clearing agents are commonly used to enhance the structural details of a sample. The current study investigates how to use it to improve the data obtained by an optical coherence tomography angiography system. A natural edible oil with no chemical base has been used for optical clearing. In-vivo testing on mice and humans yielded excellent optical clearing. Using computational techniques, the improvement in angiography signal caused by the optical clearing agent is investigated qualitatively and quantitatively. Compared to the control group, applying the edible oil-based optical clearing agent demonstrated improved vessel percentage and refined vascular signal intensity along depth.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Tomografia de Coerência Óptica
Limite:
Animals
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article