Concave P-Stereogenic Phosphorodiamidite Ligands for Enantioselective Rh(I) Catalysis.
Org Lett
; 26(11): 2202-2206, 2024 Mar 22.
Article
em En
| MEDLINE
| ID: mdl-38471122
ABSTRACT
The development of a new class of concave P-stereogenic phosphorodiamidite ligands, derived from Tröger's bases (TBs), is explored. These ligands, characterized by their remarkable stability and unique structural geometry around the P atom, are used in asymmetric Rh(I)-catalyzed additions of boronic acids to NH-isatins resulting in excellent reactivities and reasonable enantioselectivity (er up to 928).
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MEDLINE
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En
Ano de publicação:
2024
Tipo de documento:
Article