Hydrosilylation of nitriles and tertiary amides using a zinc precursor.
Org Biomol Chem
; 22(15): 3053-3058, 2024 Apr 17.
Article
em En
| MEDLINE
| ID: mdl-38545870
ABSTRACT
We report a competent and selective hydrosilylation of nitriles and tertiary amides catalyzed by the readily available zinc bis(hexamethyldisilazide) under solvent-free and mild conditions, making it a sustainable and desirable alternative to existing methods. Both protocols afforded high conversion, superior selectivity, and a broad substrate scope, from electron-withdrawing to electron-donating and heterocyclic substitutions.
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Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article