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A responsive disulfide bond switch aptamer prodrug exhibiting enhanced stability and anticancer efficacy.
Dong, Xiao; Zhang, Zhe; Zhao, Tangna; Chen, Zuyi; Wang, Jia; Xu, Liang; Zhang, Aiping.
Afiliação
  • Dong X; College of Pharmacy, Shanxi Medical University, Taiyuan 030000, China; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100080, China.
  • Zhang Z; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100080, China.
  • Zhao T; College of Pharmacy, Shanxi Medical University, Taiyuan 030000, China; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100080, China.
  • Chen Z; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100080, China.
  • Wang J; College of Pharmacy, Shanxi Medical University, Taiyuan 030000, China; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100080, China.
  • Xu L; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100080, China. Electronic address: wj24998@163.com.
  • Zhang A; College of Pharmacy, Shanxi Medical University, Taiyuan 030000, China. Electronic address: zhangap1@163.com.
Bioorg Med Chem Lett ; 104: 129729, 2024 May 15.
Article em En | MEDLINE | ID: mdl-38583786
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Aptâmeros de Nucleotídeos / Antineoplásicos Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Aptâmeros de Nucleotídeos / Antineoplásicos Idioma: En Ano de publicação: 2024 Tipo de documento: Article