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Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting.
Gruber, Christoph; Krautner, Lea; Bergant, Valter; Grass, Vincent; Ma, Zhe; Rheinemann, Lara; Krus, Ariane; Reinhardt, Friederike; Mazneykova, Lyupka; Rocha-Hasler, Marianne; Truong, Dong-Jiunn Jeffery; Westmeyer, Gil Gregor; Pichlmair, Andreas; Ebert, Gregor; Giesert, Florian; Wurst, Wolfgang.
Afiliação
  • Gruber C; Institute of Developmental Genetics, Helmholtz Munich, Oberschleißheim, Germany. christoph.gruber@helmholtz-munich.de.
  • Krautner L; TUM School of Life Sciences, Technical University of Munich, Freising, Germany. christoph.gruber@helmholtz-munich.de.
  • Bergant V; Institute of Developmental Genetics, Helmholtz Munich, Oberschleißheim, Germany.
  • Grass V; Technical University of Munich, School of Medicine and Health, Institute of Virology, Munich, Germany.
  • Ma Z; Technical University of Munich, School of Medicine and Health, Institute of Virology, Munich, Germany.
  • Rheinemann L; Institute of Virology, Technical University of Munich/Helmholtz Munich, Munich, Germany.
  • Krus A; Technical University of Munich, School of Medicine and Health, Institute of Virology, Munich, Germany.
  • Reinhardt F; Institute of Developmental Genetics, Helmholtz Munich, Oberschleißheim, Germany.
  • Mazneykova L; Institute of Developmental Genetics, Helmholtz Munich, Oberschleißheim, Germany.
  • Rocha-Hasler M; Institute of Developmental Genetics, Helmholtz Munich, Oberschleißheim, Germany.
  • Truong DJ; Institute of Virology, Technical University of Munich/Helmholtz Munich, Munich, Germany.
  • Westmeyer GG; Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich, Munich, Germany.
  • Pichlmair A; Institute for Synthetic Biomedicine, Helmholtz Munich, Oberschleißheim, Germany.
  • Ebert G; Department of Bioscience, TUM School of Natural Sciences, Technical University of Munich, Munich, Germany.
  • Giesert F; Institute for Synthetic Biomedicine, Helmholtz Munich, Oberschleißheim, Germany.
  • Wurst W; TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.
Cell Discov ; 10(1): 42, 2024 Apr 12.
Article em En | MEDLINE | ID: mdl-38609360
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article