Molecular profiling of primary endometrioid endometrial cancer and matched lung metastases: CTNNB1 mutation as a potential driver.
Gynecol Oncol Rep
; 53: 101391, 2024 Jun.
Article
em En
| MEDLINE
| ID: mdl-38633674
ABSTRACT
â¢Both primary endometrial cancers (ECs) and matched lung metastases shared a common ancestor with independent evolution at each site.â¢The two endometrioid ECs studied acquired additional mutations during the distant metastatic process.â¢Subclonal CTNNB1 hotspot mutations in the two primary ECs studied became clonal in the distant metastases.
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MEDLINE
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Ano de publicação:
2024
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Article