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In vitro Testing of Trichomonas vaginalis Drug Susceptibility: Evaluation of Minimal Lethal Concentration for Secnidazole that Correlates with Treatment Success.
Graves, Keonte J; Novak, Jan; Tiwari, Hemant; Secor, W Evan; Augostini, Peter; Muzny, Christina A.
Afiliação
  • Graves KJ; Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.
  • Novak J; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL.
  • Tiwari H; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, AL.
  • Secor WE; Division of Parasitic Diseases and Malaria, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.
  • Augostini P; Division of Parasitic Diseases and Malaria, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.
  • Muzny CA; Division of Infectious Diseases, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.
Sex Transm Dis ; 2024 Apr 30.
Article em En | MEDLINE | ID: mdl-38687328
ABSTRACT
ABSTRACT We determined the in vitro minimum lethal concentration (MLC) of secnidazole (SEC) and assessed correlation with clinical susceptibility among T. vaginalis isolates obtained from 71 women, of whom 66 were successfully treated with this medication. An MLC ≤12.5 µg/ml correlated with clinical susceptibility in this study.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article