Screening of oxidative behavior in catalytic amyloid assemblies.
Methods Enzymol
; 697: 15-33, 2024.
Article
em En
| MEDLINE
| ID: mdl-38816121
ABSTRACT
Once considered a thermodynamic minimum of the protein fold or as simply by-products of a misfolding process, amyloids are increasingly showing remarkable potential for promoting enzyme-like catalysis. Recent studies have demonstrated a diverse range of catalytic behaviors that amyloids can promote way beyond the hydrolytic behaviors originally reported. We and others have demonstrated the strong propensity of catalytic amyloids to facilitate redox reactions both in the presence and in the absence of metal cofactors. Here, we present a detailed protocol for measuring the oxidative ability of supramolecular peptide assemblies.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Oxirredução
/
Amiloide
Limite:
Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article