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New Secondary Metabolites from Marine-Derived Fungus Talaromyces minnesotensis BTBU20220184.
Wang, Weiliang; Wang, Jingjing; Song, Fuhang; Jia, Renming; Wang, Long; Xu, Xiuli; Yang, Na.
Afiliação
  • Wang W; Key Laboratory of Marine Mineral Resources and Polar Geology, Ministry of Education, School of Ocean Sciences, China University of Geosciences, Beijing 100083, China.
  • Wang J; Key Laboratory of Marine Mineral Resources and Polar Geology, Ministry of Education, School of Ocean Sciences, China University of Geosciences, Beijing 100083, China.
  • Song F; Key Laboratory of Geriatric Nutrition and Health, Ministry of Education of China, School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China.
  • Jia R; Key Laboratory of Tropical Marine Ecosystem and Bioresource, Guangxi Key Laboratory of Beibu Gulf Marine Resources, Environment and Sustainable Development, Fourth Institute of Oceanography, Ministry of Natural Resources, Beihai 536000, China.
  • Wang L; State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.
  • Xu X; Key Laboratory of Marine Mineral Resources and Polar Geology, Ministry of Education, School of Ocean Sciences, China University of Geosciences, Beijing 100083, China.
  • Yang N; CAS Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.
Mar Drugs ; 22(6)2024 May 23.
Article em En | MEDLINE | ID: mdl-38921548
ABSTRACT
Six new compounds, talamitones A and B (1 and 2), demethyltalamitone B (3), talamiisocoumaringlycosides A and B (4 and 5), and talaminaphtholglycoside (6), together with six known compounds (7-12), were isolated from the marine-derived fungus Talaromyces minnesotensis BTBU20220184. The new structures were characterized by using HRESIMS and NMR. This is the first report of isocoumaringlycoside derivatives from a fungus of the Talaromyces genus. Compounds 5, 6, and 9 showed synergistic antibacterial activity against Staphylococcus aureus.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Talaromyces / Antibacterianos Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Talaromyces / Antibacterianos Idioma: En Ano de publicação: 2024 Tipo de documento: Article