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Chemopreventive Agents from Nature: A Review of Apigenin, Rosmarinic Acid, and Thymoquinone.
Abutayeh, Reem Fawaz; Altah, Maram; Mehdawi, Amani; Al-Ataby, Israa; Ardakani, Adel.
Afiliação
  • Abutayeh RF; Faculty of Pharmacy, Applied Science Private University, Amman 11937, Jordan.
  • Altah M; School of Pharmacy, Al-Qadisiyah College, Amman 11118, Jordan.
  • Mehdawi A; School of Pharmacy, Al-Qadisiyah College, Amman 11118, Jordan.
  • Al-Ataby I; Faculty of Pharmacy, Applied Science Private University, Amman 11937, Jordan.
  • Ardakani A; College of Pharmacy, Amman Arab University, Amman 11953, Jordan.
Curr Issues Mol Biol ; 46(7): 6600-6619, 2024 Jun 27.
Article em En | MEDLINE | ID: mdl-39057035
ABSTRACT
Cancer, a major challenge to global health and healthcare systems, requires the study of alternative and supportive treatments due to the limitations of conventional therapies. This review examines the chemopreventive potential of three natural compounds rosmarinic acid, apigenin, and thymoquinone. Derived from various plants, these compounds have demonstrated promising chemopreventive properties in in vitro, in vivo, and in silico studies. Specifically, they have been shown to inhibit cancer cell growth, induce apoptosis, and modulate key signaling pathways involved in cancer progression. The aim of this review is to provide a comprehensive overview of the current research on these phytochemicals, elucidating their mechanisms of action, therapeutic efficacy, and potential as adjuncts to traditional cancer therapies. This information serves as a valuable resource for researchers and healthcare providers interested in expanding their knowledge within the field of alternative cancer therapies.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2024 Tipo de documento: Article