Near-Infrared Fluorescent Probe for the Detection of Cysteine.
Appl Spectrosc
; 78(7): 744-752, 2024 Jul.
Article
em En
| MEDLINE
| ID: mdl-39096170
ABSTRACT
Hemicyanine dyes are an ideal structure for building near-infrared fluorescent probes due to their excellent emission wavelength properties and biocompatibility in biological imaging field. Developing a near-infrared fluorescent probe capable of detecting cysteine (Cys) was the aim of this study. A novel developed fluorescent probe P showed high selectivity and sensitivity to Cys in the presence of various analytes. The detection limit of P was found to be 0.329â
µM. The MTT assay showed that the probe was essentially non-cytotoxic. Furthermore, the probe was successfully used as cysteine imaging in living cells and mice.
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Base de dados:
MEDLINE
Assunto principal:
Cisteína
/
Corantes Fluorescentes
Limite:
Animals
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Humans
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article