Measurement of retinal blood flow precision in the human eye with multimodal adaptive optics imaging.
Biomed Opt Express
; 15(8): 4625-4641, 2024 Aug 01.
Article
em En
| MEDLINE
| ID: mdl-39346998
ABSTRACT
Impaired retinal blood flow (RBF) autoregulation plays a key role in the development and progression of several ocular diseases, including glaucoma and diabetic retinopathy. Clinically, reproducible RBF quantitation could significantly improve early diagnosis and disease management. Several non-invasive techniques have been developed but are limited for retinal microvasculature flow measurements due to their low signal-to-noise ratio and poor lateral resolution. In this study, we demonstrate reproducible vessel caliber and retinal blood flow velocity measurements in healthy human volunteers using a high-resolution (spatial and temporal) multimodal adaptive optics system with scanning laser ophthalmoscopy and optical coherence tomography.
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MEDLINE
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En
Ano de publicação:
2024
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Article