Some physical properties of K antigens of Escherichia coli related to their biological activity.
Infect Immun
; 4(1): 6-11, 1971 Jul.
Article
em En
| MEDLINE
| ID: mdl-5005287
ABSTRACT
The ability of K antigens from Escherichia coli to inhibit the agglutination of sheep red cells by rabbit antibody has been taken as a measure of the ability of such antigens to render strains of E. coli O-inagglutinable, resistant to complement and to phagocytosis, and to increase their virulence for mice. Analysis of K antigens by chromatography on Sepharose and diethylaminoethyl cellulose columns and by immunoelectrophoresis suggested that agglutination-inhibiting activity was directly related to molecular size rather than charge. The effect of alkali treatment showed inhibitory activity to be independent of K-specific antigenic determinants and confirmed its relation to molecular weight.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Escherichia coli
/
Antígenos de Bactérias
Limite:
Animals
Idioma:
En
Ano de publicação:
1971
Tipo de documento:
Article