Effect of dehydroepiandrosterone on hereditary angioedema.
Klin Wochenschr
; 61(14): 715-7, 1983 Jul 15.
Article
em En
| MEDLINE
| ID: mdl-6224964
ABSTRACT
Hereditary angioneurotic edema (HAE) is a complement-related clinical disorder with a deficiency of the C1 esterase inhibitor protein. Eight patients with severe attacks of the disease were treated with the adrenal "androgen" dehydroepiandrosterone sulphate (DS). Steroid therapy for 3-28 months resulted in dramatic improvement in their clinical state and a moderate increase in the serum concentration of C1 inhibitor. There was a significant increase in the serum level of either unconjugated dehydroepiandrosterone (D) or of DS during treatment.
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Base de dados:
MEDLINE
Assunto principal:
Desidroepiandrosterona
/
Angioedema
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1983
Tipo de documento:
Article