Iron overload and lysosomal stability in beta zero-thalassaemia intermedia and trait: correlation between serum ferritin and serum N-acetyl-beta-D-glucosaminidase levels.
Scand J Haematol
; 33(3): 252-5, 1984 Sep.
Article
em En
| MEDLINE
| ID: mdl-6505627
ABSTRACT
Increased iron storage represents a characteristic condition in patients with beta zero-thalassaemia intermedia. Iron overload is an important factor in cellular damage. Recent studies have shown an enhanced lysosomal fragility due to increased iron storage. 13 patients with beta-thalassaemia intermedia, aged 17-44 years, were studied. Both serum ferritin and serum N-acetyl-beta-D-glucosaminidase levels were evaluated in all subjects studied. A significant linear correlation (P less than 0.05) between serum ferritin and serum N-acetyl-beta-D-glucosaminidase levels were found.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Acetilglucosaminidase
/
Talassemia
/
Ferritinas
/
Hexosaminidases
/
Ferro
/
Lisossomos
Limite:
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1984
Tipo de documento:
Article