Eosinophilic granulocytes as a possible source of vitamin B12-binding protein.
Scand J Haematol
; 31(5): 507-9, 1983 Nov.
Article
em En
| MEDLINE
| ID: mdl-6580720
ABSTRACT
Leucocyte B12 and B12-binding capacity were measured by Simultrac radioassay in eosinophilic granulocytes, neutrophilic granulocytes and leucocytes obtained from patients with chronic granulocytic and lymphocytic leukaemia. It is shown that (a) eosinophils are a possible source of B12-binding protein similar to neutrophils and (b) granulocytes in myeloproliferative disorders and normal neutrophils have similar B12 and B12-binding capacity indicating that increased B12 and B12-binding capacity in myeloproliferative disorders arise from an increase in myeloid cell turnover.
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Base de dados:
MEDLINE
Assunto principal:
Transcobalaminas
/
Eosinofilia
/
Eosinófilos
Limite:
Humans
/
Male
/
Middle aged
Idioma:
En
Ano de publicação:
1983
Tipo de documento:
Article