Congenitally athymic nude (nu/nu) mice have Thy-1-bearing immunocompetent helper T cells in their peritoneal cavity.
J Exp Med
; 151(4): 965-8, 1980 Apr 01.
Article
em En
| MEDLINE
| ID: mdl-6966314
Heavily irradiated peritoneal cells (PC) from congenitally athymic nude (nu/nu) mice markedly restored the impaired in vitro antibody response of nu/nu spleen cells to sheep erythrocyte antigens (T-dependent antigen), whereas irradiated spleen or lymph node cells from nu/nu mice had no effect on the response. This activity of the irradiated PC of nu/nu mice was completely abolished by treatment with anti-Thy-1.2 antiserum plus normal guinea pig serum (C') and is, therefore, attributable to a function of matured T cells.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Líquido Ascítico
/
Linfócitos T
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Cooperação Linfocítica
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Camundongos Nus
Limite:
Animals
Idioma:
En
Ano de publicação:
1980
Tipo de documento:
Article