Enzyme reactions in the presence of cyclodextrins: biosensors and enzyme assays.
Trends Biotechnol
; 13(11): 457-63, 1995 Nov.
Article
em En
| MEDLINE
| ID: mdl-7488360
ABSTRACT
Cyclodextrins, macrocyclic carbohydrates with apolar internal cavities, can form complexes with, and solubilize many normally water-insoluble compounds. Ferrocene and its derivatives, tetrathiafulvalene and tetramethylbenzidine, can function as redox mediators, but are insoluble in water; when they are complexed with cyclodextrins, they can be used in enzymatic assays and in the construction of mediated biosensors. In addition, the solubilization of polynuclear aromatic hydrocarbons (PAHs), including the potent carcinogen benzo[a]pyrene, by cyclodextrins has enabled the detection of these important environmental contaminants.
Buscar no Google
Base de dados:
MEDLINE
Assunto principal:
Técnicas Biossensoriais
/
Ciclodextrinas
/
Enzimas
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article