The genetic basis of quantitative variation: numbers of sensory bristles of Drosophila melanogaster as a model system.
Trends Genet
; 11(12): 464-70, 1995 Dec.
Article
em En
| MEDLINE
| ID: mdl-8533161
ABSTRACT
The numbers of sensory hairs of Drosophila melanogaster present an ideal model system to elucidate the genetic basis of morphological quantitative variation. Loci affecting bristle number can be identified and their properties studied by accumulating spontaneous mutations, by P element mutagenesis, by mapping factors causing divergence between selection lines and by the association of phenotype variation with molecular variation at candidate neurogenic loci. The consensus emerging from the application of all approaches is that much of the mutational and segregating variation affecting bristle number is attributable to alleles with large phenotype effects at a small number of candidate loci.
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Base de dados:
MEDLINE
Assunto principal:
Variação Genética
/
Genes de Insetos
/
Drosophila melanogaster
/
Mutação
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article