[Marine fish oil in the prevention and treatment of cardiovascular diseases]. / Zhir morskikh ryb v profilaktike i lechenii serdechno-sosudistykh zabolevanii.

ABSTRACT

Diets containing different ratios of omega 6 omega 3- polyunsaturated fatty acids (PUFA) were studied for their hypolipidemic, antiatherogenic, thrombolytic, and antihypertensive effects in 448 patients with coronary heart disease, familial hyperlipoproteinemia, essential hypertension. Optimizing the omega 6 omega 3-PUFA ratios in the antiatherosclerotic diet of patients with cardiovascular diseases during inpatient course treatment was found to promote the formation of combined therapeutical effects of a diet. This is caused by changes in the fatty acid composition of cytomembranes and, apparently by lipid-protein interactions that affect the activity of a complex of lipolytic membrane-binding enzymes of different types of cells.