Cytokine production during infection with Hymenolepis diminuta in BALB/c mice.
Int J Parasitol
; 27(7): 855-9, 1997 Jul.
Article
em En
| MEDLINE
| ID: mdl-9279590
ABSTRACT
Levels of the cytokines IFN-gamma, IL-2, IL-3, IL-4 and IL-5 were monitored in cells from the mesenteric lymph nodes (MLN) of BALB/c mice infected with Hymenolepis diminuta after stimulation in vitro with Con-A. Infection was associated with an increased production of IL-3, IL-4 and IL-5 and a low production of IFN-gamma, indicating the preferential activation of a Th2 response. It is suggested that this reflects the purely lumenal development of this worm. The results are discussed in relation to effector mechanisms known to be involved in immunity to intestinal helminths.
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Base de dados:
MEDLINE
Assunto principal:
Interleucinas
/
Interferon gama
/
Himenolepíase
Limite:
Animals
Idioma:
En
Ano de publicação:
1997
Tipo de documento:
Article