Pathophysiology and mechanisms of acute ischemic stroke. The NINDS rt-PA Stroke Study Group.
J Neurosci Nurs
; 29(6): 356-60, 1997 Dec.
Article
em En
| MEDLINE
| ID: mdl-9479656
ABSTRACT
Stroke is a leading cause of death and disability among Americans. The recent US Food and Drug Administration approval of recombinant tissue plasminogen activator (rt-PA, Activase) for the treatment of acute ischemic stroke offers the first proven therapy to reverse or ameliorate stroke symptoms. rt-PA is thought to restore circulation in the patient with acute ischemic stroke by dissolving an occluding thrombus or embolus. A basic understanding of cerebral circulation and the mechanism by which stroke compromises brain tissue is fundamental to appreciating this new therapy. The importance of prompt stroke diagnosis and treatment cannot be underestimated.
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Base de dados:
MEDLINE
Assunto principal:
Proteínas Recombinantes
/
Ativadores de Plasminogênio
/
Transtornos Cerebrovasculares
/
Ativador de Plasminogênio Tecidual
Tipo de estudo:
Etiology_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
1997
Tipo de documento:
Article