M genotyping and DNA fingerprinting of Streptococcus pyogenes isolates from an area of central Italy.
Epidemiol Infect
; 121(1): 77-84, 1998 Aug.
Article
em En
| MEDLINE
| ID: mdl-9747758
ABSTRACT
M protein gene typing was used to analyse Streptococcus pyogenes clinical isolates collected between 1983 and 1995 in an area of central Italy from patients presenting different types of infections; the same isolates were also characterized by means of DNA fingerprinting. M type 1 was the most common (50% of study strains), followed by M types 4, 12 and 6. The proportion of M type 12 decreased with time, whereas M type 1 increased, in agreement with data obtained in many different areas. Most invasive strains belonged to types M1 (30%) and M12 (30%); on the other hand, the M1 type did frequently occur also among non-invasive isolates. DNA fingerprinting showed a correlation between M types and DNA patterns. This report provides epidemiological information from a geographic area not sampled recently, and further shows the usefulness of the M genotyping technique, which offers potential advantages over conventional serological typing methods.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Infecções Estreptocócicas
/
Streptococcus pyogenes
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DNA Bacteriano
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Ano de publicação:
1998
Tipo de documento:
Article