الملخص
The effect of betamethasone on the outcome in moderate to severe tetanus was studied in a randomised, double blind, placebo controlled study in 22 patients. The mortality rate was reduced by 36.1% with the addition of corticosteroids to the regime of treatment. Betamethasone did not alter the duration of intensive care in those requiring it, but reduced the need for tracheostomy and ventilation. The mean daily dose of diazepam required was not significantly different between the two groups and there was no increase in the incidence of infections in the betamethasone group.
الموضوعات
Adult , Betamethasone/administration & dosage , Developing Countries , Double-Blind Method , Female , Humans , India , Infusions, Intravenous , Male , Middle Aged , Prospective Studies , Survival Rate , Tetanus/drug therapyالملخص
A prospective study of 11 cases of Clistanthus collinus leaf poisoning was undertaken to evaluate the mechanism of hypokalaemia that occurs in these cases. Continuous cardiac monitoring was done. Ventricular ectopics, ventricular tachycardia and fibrillation were the important arrhythmias. No atrioventricular blocks or other significant bradyarrhythmias were noted. The renal potassium loss was found to be very high (120 +/- 87.95 mEq/L) even in the presence of hypokalaemia and in spite of continuing drop in serum potassium concentration. Metabolic study established that renal potassium leak is the mechanism by which hypokalaemia was mediated.
الموضوعات
Adolescent , Adult , Arrhythmias, Cardiac/etiology , Child , Female , Humans , Hypokalemia/blood , Male , Middle Aged , Plant Poisoning/blood , Potassium/blood , Prospective Studiesالملخص
Kawasaki and associates first described a mucocutaneous lymph node syndrome from Japan. Since then this febrile illness has been reported from several countries. The patient described in this report had all the clinical manifestations of this entity excepting coronary aneurysms.