الملخص
<p><b>OBJECTIVE</b>To probe the theoretical basis of acupuncture by investigating the relationship of 'true' acupuncture and 'sham' acupuncture, with the cerebral functions observed by means of functional magnetic resonance imaging (fMRI).</p><p><b>METHODS</b>Eighteen healthy volunteers with normal vision were randomly divided into group A and B. Firstly, all the volunteers received 'sham' acupuncture, and then acupuncture was given at Guangming (GB 37) and Taichong (LR 3) in the group A, and Fenglong (ST 40) and Xiangu (ST 43) were given in the group Activation in the thalamus, B.A 1.5 Tesla Vision Scanner (Siemens, Erlangen) was used for imaging.</p><p><b>RESULTS</b>Activation in the thalamus, the red nucleus, the sulcus lateralis and the parieto-temporal cortex proved that there was a significant difference between true acupuncture and sham acupuncture in the GLM test.</p><p><b>CONCLUSION</b>Acupuncture does not have effects on the visual cortex, but it has active action on the insula sulcus lateralis and the parieto-temporal cortex, which are involved in painful and somatosensory stimulation.</p>
الموضوعات
Humans , Acupuncture , Acupuncture Points , Acupuncture Therapy , Brain , Magnetic Resonance Imagingالملخص
<p><b>OBJECTIVE</b>To observe relative effects of acupuncture at Guangming (GB 37) and Taichong (LR 3) in central different regions.</p><p><b>METHODS</b>Nineteen healthy volunteers were randomly divided into 3 groups: group I (n=7) received visual stimulation and acupuncture at one side; group II (n=6) received visual stimulation and acupuncture at both sides; and group III (n=6) received acupuncture at both sides. Functional magnetic resonance imaging (fMRI) was used to investigate reactions of the different visual cortexes and relative cerebral regions in acupuncture at Guangming (GB 37) and Taichong (LR 3).</p><p><b>RESULTS</b>There was no significant change in blood oxygen saturation levels in the visual cortex at visual stimulation and insertion of the needle, but there were changes in blood oxygen saturation level in relative cerebral regions when continuous stimulation was given to one-side or both sides.</p><p><b>CONCLUSION</b>Acupuncture at one-side or both sides can improve blood oxygen saturation level in relative cerebral regions, which is not related with manipulation method and visual stimulation.</p>