الملخص
Narcolepsy with cataplexy (NC) is associated with hypocretin deficiency, and is thought to be an autoimmunity condition. The mean age at onset is estimated to be in the early 20s. Recent papers have addressed the response to immunotherapies in NC, with challenging results. We report a case of late-onset NC in a patient who did not benefit from early intravenous high-dose immunoglobulin (IVIg) therapy. This is the first reported attempt at using IVIg to treat an NC patient in Korea.
الموضوعات
Humans , Autoimmunity , Cataplexy , Immunoglobulins , Immunoglobulins, Intravenous , Immunotherapy , Intracellular Signaling Peptides and Proteins , Korea , Narcolepsy , Neuropeptides , Orexinsالملخص
No abstract available.
الموضوعات
Amines , Cyclohexanecarboxylic Acids , gamma-Aminobutyric Acid , Hiccupالملخص
Spontaneous intracranial hypotension (SIH) is characterized by orthostatic headache, diffuse dural thickening, and enhancement in MRI associated with low cerebrospinal fluid pressure. While SIH causes several complications such as subdural hematoma, cranial nerve palsies, and altered consciousness, cerebral venous thrombosis caused by SIH has been rarely described. We report a patient presenting with generalized tonic-clonic seizure that was probably caused by cortical vein thrombosis that had developed after SIH.