1.
Acta Pharmaceutica Sinica B
; (6): 505-519, 2021.
مقالة
ي الانجليزية
| WPRIM
| ID: wpr-881150
الملخص
Psoriatic arthritis (PsA) is a complicated psoriasis comorbidity with manifestations of psoriatic skin and arthritic joints, and tailoring specific treatment strategies for simultaneously delivering different drugs to different action sites in PsA remains challenging. We developed a need-based layered dissolving microneedle (MN) system loading immunosuppressant tacrolimus (TAC) and anti-inflammatory diclofenac (DIC) in different layers of MNs,